Dr. Starpoli's Blog

Incisionless Anti-reflux Therapy: a chance to stop your reflux drugs.

Posted by Anthony A. Starpoli, MD on Jun 5, 2019 10:54:02 AM

Gastroesophageal Reflux Disease (GERD) is a life-affecting condition that affects as many as 20% of the population. Given the prevalence of GERD, the quest for suitable treatment methods has been a relentless one— but often to little effect.

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Anthony A. Starpoli, MD | www.starpoli.com

Obesity, Reflux, fundoplication, atypical reflux, heartburn, EsophyX, incisionless surgery, GERD Awareness Week

Concerns about PPI Therapy For GERD

Posted by Anthony A. Starpoli, MD on Jul 28, 2018 9:02:24 PM

Acid reflux, generally stated as Gastro-Esophageal Reflux Disease (GERD), affecting around one-third of the American population. This disorder arises when the uppermost portion of the digestive region is not working accurately, causing stomach contents to move back into the esophagus. The most common symptoms of this disease is heartburn, the sensation of liquid or food coming up into the throat and a sour taste. The most effective therapy for relieving the symptoms of GERD is proton pump inhibitors (PPIs) such as lansoprazole, esomeprazole, and omeprazole. This is a class of medications which have emerged as the most effective therapy, improving life quality, healing and preventing the damage to the esophagus (1). PPIs work by obstructing an enzyme in the lining of the stomach which is essential for acid secretion. Side effects which some patients report comprise a headache, diarrhea, constipation, abdominal pain, and nausea. They usually resolve on their own and patients can usually carry on taking their PPI medication (2). A different, incisionless, transoral endoscopic treatment has been developed to help correct the mechanical flaws of the valve between the lower esophagus and stomach that cause GERD.

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Anthony A. Starpoli, MD | www.starpoli.com

acid reflux, heartburn, EsophyX

EsophyX TIF Procedure is Superior to Maximum Dose PPI Therapy

Posted by Anthony Starpoli on May 30, 2013 12:30:00 AM

As reported by Medscape, according to research presented at the Digestive Disease Week meeting, “patients with gastroesophageal reflux disease (GERD) might benefit more from transoral incisionless fundoplication (TIF) than from continued treatment with proton-pump inhibitors (PPIs).” The study’s lead author Karim Trad, MD, said, “In this study, transoral incisionless fundoplication was superior to maximal-dose PPIs in eliminating daily troublesome typical and atypical symptoms in selected patients.” Dr. Trad added that the findings “establish for the first time that, for some patients, the procedure is better than maximal-dose PPI therapy for controlling a range of GERD symptoms.”

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Anthony A. Starpoli, MD | www.starpoli.com

hiatal hernia, fundoplication, LINX, GERD, atypical reflux, EsophyX, incisionless surgery, esophageal cancer

Refluxology: The Study of GERD

Posted by Anthony Starpoli on Jul 21, 2012 11:36:00 AM

So, you think you have acid reflux?  What is acid reflux?  Why is it called acid reflux?

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Anthony A. Starpoli, MD | www.starpoli.com

Obesity, GERD, atypical reflux, nonacid reflux, heartburn, EsophyX, incisionless surgery, Barrett's Esophagus

New Surgical Therapy for GERD: The LINX Magnetic Bracelet

Posted by Anthony Starpoli on Apr 23, 2012 9:27:00 AM

A new laparoscopic therapy for reflux has been recently approved for the treat of reflux.  The procedure requires laparoscopic surgery (small incisions in the abdomen) in order to place this new device at the level of the lower esophageal sphincter.  Certain limitations will occur as the result of this procedure as will be discussed.

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Anthony A. Starpoli, MD | www.starpoli.com

Reflux, hiatal hernia, TIF, LINX, GERD, atypical reflux, heartburn, EsophyX, Barrett's Esophagus

FDA Warns: Reflux Drug Therapy & Increased C. difficle Diarrhea

Posted by Anthony Starpoli on Mar 13, 2012 2:51:00 AM

Several news agencies recently reported concerns of the FDA over the increased risk of Clostridium difficle diarrheal illness in patients using acid lowering antireflux drugs in the treatment of gastroesophageal reflux disease (GERD).

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Anthony A. Starpoli, MD | www.starpoli.com

c. difficile, hiatal hernia, GERD, atypical reflux, EsophyX

Hybrid GERD Surgery Performed at NYU Langone Medical Center

Posted by Anthony Starpoli on Oct 14, 2011 11:40:00 AM

On September 7th and October 13th, 2011, the first two combined laparoscopic and transoral antireflux procedures were performed at the New York Univerisity Langone Medical Center in New York City.

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Anthony A. Starpoli, MD | www.starpoli.com

Reflux, hiatal hernia, TIF, fundoplication, GERD, LPR, atypical reflux, heartburn, EsophyX, Barrett's Esophagus

Much Greater Risk for Clostridium difficle with Reflux Therapy

Posted by Anthony Starpoli on Oct 7, 2011 6:47:00 PM

In a retrospective study from Japan, the chronic use of proton pump inhibitors (PPIs), often used in the treatment of GERD, was found to be associated with a greater than 3-fold increased risk of developing Clostridium difficile–associated diarrhea (CDAD), Takatoshi Kitazawa, MD, assistant professor at Teikyo University in Tokyo, Japan, reported during a poster session at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy.

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Anthony A. Starpoli, MD | www.starpoli.com

Reflux, diarrhea, TIF, GERD, nonacid reflux, EsophyX

Doctor Radio-SIRIUSXM and NYU Features Dr. Starpoli and TIF

Posted by Anthony Starpoli on Jun 21, 2011 7:47:00 AM


Today Dr. Starpoli will be hosted on the Doctor Radio show to discuss GERD and transoral incisionless fundoplication with EsophyX.  This procedure serves as an alternative to chronic, long-term drug therapy that millions of people world-wide must take to control their reflux.  Given new information on the perils of long-term drug therapy for reflux, antireflux surgery is being more considered every day.

Doctor Radio is a groundbreaking 24/7 national radio channel featuring live,

call-in shows hosted by leading NYU Langone Medical Center doctors from a vast

array of fields including: child psychology and psychiatry; sexual health;

plastic surgery; emergency room medicine; cancer; heart health; women's health;

dermatology; pediatrics; men's health; diet and nutrition; sports medicine;

psychiatry; and more.


SIRIUSXM and NYU have built a state-of-the-art broadcasting studio

in the lobby of the Manhattan-based NYU Langone Medical Center, bringing

listeners right into the middle of the medical world.

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Anthony A. Starpoli, MD | www.starpoli.com

TIF, doctor radio, GERD, atypical reflux, heartburn, EsophyX, Barrett's Esophagus

Antireflux Surgery and GERD Drug Therapy Achieve Similar Results

Posted by Anthony Starpoli on Jun 4, 2011 11:43:00 AM


 
A report was published in the May 18 issue ofA report was published in the May 18 issue of Journal of the American Medical Association. In, what is referred to as the LOTUS (Long-Term Usage of Esomeprazole vs Surgery for Treatment of Chronic GERD) study, remission rates at five years were 92% (95% CI 89 to 96) for patients on esomeprazole and 85% (95% CI 81 to 90, P=0.048) for those who had laparoscopic antireflux surgery, according to Jean-Paul Galmiche, MD, of Nantes University in France, and colleagues. 

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Anthony A. Starpoli, MD | www.starpoli.com

Reflux, TIF, fundoplication, GERD, nonacid reflux, EsophyX