Dr. Starpoli's Blog

Concerns about PPI Therapy For GERD

Posted by Anthony A. Starpoli, MD on Jul 28, 2018 9:02:24 PM

Acid reflux, generally stated as Gastro-Esophageal Reflux Disease (GERD), affecting around one-third of the American population. This disorder arises when the uppermost portion of the digestive region is not working accurately, causing stomach contents to move back into the esophagus. The most common symptoms of this disease is heartburn, the sensation of liquid or food coming up into the throat and a sour taste. The most effective therapy for relieving the symptoms of GERD is proton pump inhibitors (PPIs) such as lansoprazole, esomeprazole, and omeprazole. This is a class of medications which have emerged as the most effective therapy, improving life quality, healing and preventing the damage to the esophagus (1). PPIs work by obstructing an enzyme in the lining of the stomach which is essential for acid secretion. Side effects which some patients report comprise a headache, diarrhea, constipation, abdominal pain, and nausea. They usually resolve on their own and patients can usually carry on taking their PPI medication (2). A different, incisionless, transoral endoscopic treatment has been developed to help correct the mechanical flaws of the valve between the lower esophagus and stomach that cause GERD.

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Anthony A. Starpoli, MD | www.starpoli.com

acid reflux, heartburn, EsophyX