Heartburn,
Reflux & GERD
Everyone
occasionally has heartburn. This occurs when stomach acid
flows backward into the esophagus, the food pipe that carries
food to the stomach. People usually experience heartburn
after meals as a burning sensation or pain behind the breast bone.
Often, regurgitation of food and bitter-tasting stomach
acid accompanies heartburn. Antacids or milk temporarily
relieves heartburn for most people.
Why
Does Heartburn Occur?
To understand heartburn, let us look at the body's anatomy.
The esophagus carries food and liquid to the stomach. A
sphincter, or muscular valve, is located at the end of the
esophagus at the border between the esophagus and stomach. Known as the lower esophageal sphincter (LES)
this muscle contracts much the same as the anus does. The
sphincter should maintain a certain pressure to keep the
end of the esophagus closed so that stomach juices are not
admitted. The LES muscle should only open when food is passed
into the stomach.
However,
the LES muscle does not always work perfectly.
It is felt that the problem is with inappropriate, transient relaxations of this
sphincter valve that result in reflux. Sphincter function can be
easily overcome by a number of factors, the most common
being eating a large meal. Along with swallowed air, a large
meal causes an upward pressure in the stomach to rise, thereby
overpowering the LES muscle. Other factors that reduce the
LES pressure and allow reflux are:
-
Nicotine
(cigarettes)
-
Fried
or fatty foods
-
Chocolate
-
Coffee
-
Citrus
fruits and juices
-
Peppermint
-
Pregnancy
-
Lying
flat
- Hiatus
hernia
- Certain
prescription medications
Is
Heartburn: Common, but is it serious?
Heartburn and reflux are extremely common, with 10 percent
of the population experiencing them daily. Twenty-five percent
of pregnant women have heartburn. Even though heartburn
is common, it is rarely life threatening. Severe cases,
however, can result in injury to the lower esophagus that
requires treatment.
What
is a Hiatus Hernia?
The esophagus passes through a muscle, called the diaphragm,
which separates the lungs from the abdomen. When the opening
in the diaphragm enlarges, a portion of the stomach can
protrude (herniate) through it into the chest. This is called
a hiatal hernia. A persistent hiatal hernia may produce
significant heartburn. Many people with a hiatus hernia
do not experience heartburn. However, 40-50% of patients
with a hiatal hernia have reflux. A hiatal hernia and GERD
can occur independently from one another.
Complications
Besides heartburn, the major problems that can develop with
long-term reflux are:
-
Chronic
bleeding and anemia.
-
Scar
formation and narrowing of the lower esophagus ehich may
cause swallowing difficulty. A stricture usually can
be treated by dilatation.
-
Barretts
Esophagus, which occurs when long-term reflux irritates
the lower esophagus so that the stomach lining actually
grows into the esophagus. In these cases, there is a small,
but definite, risk of a subsequent malignancy. Barrett's
Esophagus requires periodic monitoring with endoscopy
to detect early cancer states. The BARRX ablation procedure
is a safe and effective treatment for Barrett's Esophagus,
you can read more here.
-
Lung
problems when reflux of stomach fluid trickle into
the breathing tubes, causing wheezing, bronchitis and
even pneumonia. This often occurs at night when a patient
is lying down.
Treatment
General measures the patient can take to reduce reflux are:
-
Eat
smaller and more frequent meals.
-
Avoid
eating before going to bed.
-
Eliminate
excessive bending, lifting, abdominal exercises, girdles
and tight belts, all of which increase abdominal pressure
and provoke reflux.
-
If
overweight, lose weight. Being overweight promotes
reflux.
-
Eliminate
the use of nicotine (cigarettes), fatty foods, alcohol,
all coffees (yes-including decaf), chocolate and peppermint.
-
Elevate
the head of the bed 8" to 10" by placing
pillows or a wedge under the upper part of the mattress.
In this way, gravity keeps stomach juices out of the esophagus
while the patient sleeps. It is not enough to use two
pillows under the head.
-
Prescription
medications - check with the physician regarding side
effects of prescription drugs. Some drugs actually lower
the strength of the LES muscle. These include anti-spasmotics
(Levsin, Librax, Bentyl), calcium channel blocks (Procardia,
Cardizem, Calan, Isoptin), anti-depressants (Elavil, Doxepia)
and others.
Diagnosis
The primary tests used to diagnose reflux are:
-
Upper
GI Endoscopy- The patient is mildly sedated and a
flexible videoscope is inserted into the esophagus to
visually inspect it and the stomach
-
Upper
GI Series- The patient drinks liquid barium and x-rays
are taken of the esophagus and stomach showing how they
function..
-
Esophageal
manometry- This test measures the pressure within
the esophagus, especially the LES pressure.
-
24
hour Ambulatory combined pH (acid)and impedance Monitoring- Ambulatory combined
pH and impedance monitoring, called the Sleuth System is the new gold standard for
objectively assessing nonacid as well acid reflux activity and can confirm
significant gastroesophageal reflux disease. Studies show
that patients with persistent symptoms on medical therapy have nonacid
reflux 40% of the time. pH and impedance reflux monitoring
is usually performed prior to any antireflux procedure and is used to
diagnose difficult or atypical reflux cases. A tiny tube is placed through the nose
and into the esophagus (food tube) above the lower esophageal
sphincter. The test runs for 24 hours and measures the
number of times acid enters the esophagus. Wireless technology
called The BRAVO System is also available. Click here
to learn more about BRAVO. BRAVO is a wireless transmitting
capsule which is placed usually following endoscopy. It will measure acid reflux
activity only for 48 hours and the capsule will usually fall
off within 3 to 5 days and is passed. Bravo offers longer
data collection times and better patient comfort, but is limited
in that it only measures acid reflux activity and will not measure
nonacid reflux. The newer Sleuth pH-impedance reflux testing that measures nonacid and acid
reflux is available through Greenwich Village
Gastroenterology at St. Vincent's Hospital in Manhattan
(New York).
Monitoring
for Acid Reflux Detection
-
Other
Treatments include:
Antacids- These can and should be used more often.
Generally, antacids should be taken 30 to 60 minutes after
eating and at bedtime. Liquids are preferred to tablets,
with the strongest being Maalox II, Mylanta II, Gelusil
II and Extra Strength Riopan.
-
Alginic
Acid and Antacids- Two products, Gaviscon and Algicon,
place a layer of foam over the fluid in the stomach to
prevent reflux. These tablets should be chewed well and
used 30 to 60 minutes after eating and at bedtime.
-
Drugs-
Medicines are now available that effectively reduces and
even eliminates the secretion of stomach acid and increases
the strength of the LES muscle. These medicines represent
the most important method of treating reflux next to surgical
or futuristic nonsurgical methods of correcting reflux.
Other medications such as Reglan ( generic- metoclopramide),
and Urecholine (generic- bethanecol) directly increase
the strength of the LES muscle. Unfortunately, these drugs
have certain adverse side effects and are not always helpful.
Propulsid (generic- Cisapride) has been taken off the
market due to it's cardiac side effects.
-
Endoscopic
Surgery- Surgery can treat reflux. Those patients
who are dependent on acid lowering agents may entertain
an antireflux procedure. There are few patients who do
not repsond to medical therapy and benefit from antireflux
prcedures. Generally, however, a failure of medical therapy
is not an indiction for surgery. Prior to any corrective
procedure, a patient must undergo an extensive evaluation.
The objective of this surgery is to strengthen the LES
muscle. Successful surgery greatly relieves and can correct
severe reflux and heartburn. A method of performing anti-reflux
surgery is by laparoscopic technique whereby the surgery
is accomplished through tiny holes in the belly button
and upper abdomen. Recovery is quicker with this technique.
However, the procedure is still an invasive surgery which
has certain inherent risks and potential complications,
and requires the use of general anesthesia. This operation
should only be performed by qualified surgeons thoroughly
familiar with it.
As
director of the GERD unit at St. Vincents Hospital Catholoic
Medical Center of New York, I am pleased to announce that
nonsurgical, endoscopic methods for the treatment of
reflux are now available. The procedures, referred to
as EndoCinch, and the NDO Plicator, involve the
use of devices that intensify the antireflux barrier at
the level of the lower sphincter valve between the esophagus
and stomach.
This
The NDO Plicator and EndoCinch employ a suturing system
to create pleats in order the improve the lower valve function.
The
team at St. Vincents Hospital and Medical Center of New
York was the first center in New York to offer EndoCinch,
and the NDO Plicator . These procedures are also performed
at Lenox Hill Hospital in Manhattan, New York. Working in
conjunction with the developers and manufacturers of the
endoscopic reflux therapy devices, The GERD Unit at St.
Vincents Hospital Catholic Medical Center has taken the
lead in the diagnosis and management of gastroesophageal
reflux disease.
In
Summary
Heartburn occurs so commonly that it is normal for everyone
to experience it sometime. However, when heartburn is persistent,
it needs to be evaluated, and long-term follow up care is
often required. Heartburn occurring two times weekly or
more warrants a medical evaluation.
Medical
treatment along with lifestyle changes are usually very
effective and can prevent complications. For those patients
requiring chronic medical therapy, an antireflux procedure,
such as EndoCinch or the NDO Plicator, offers a viable and
usually successful alternative.
To
learn more about your treatment options you may contact
our offices at 1-877-4GERDMD or 212-673-2721 or 845-471-1354.
Additional
Resource Material
Learn
more about EndoCinch!

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